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1.
Body Image ; 44: 78-92, 2023 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-36549091

RESUMEN

Muscle dysmorphia (MD) is a mental disorder characterised by preoccupation that one lacks muscularity and/or leanness, leading to substantial functional impairment. This article is the second of a two-part qualitative study examining the phenomenology of MD among 29 adults with diagnosed MD. We used reflexive thematic analysis to generate five themes which capture the role of exercise in the lives of people with MD. In summary, participants were highly motivated by a constant desire to progress their strength and appearance, and bad or missed workouts which threatened to derail their progress were associated with acute mental health impairment. Most participants scheduled rest days and modified workouts, both for muscle building-related goals and to reduce the risk of injuries, but often continued to exercise when sick. Alongside appearance-driven motivations, participants reported exercising for a variety of non-appearance-related reasons, including to structure their daily lives, boost self-esteem, regulate affect, and gain a sense of control from being able to manipulate their body composition. Exercise was often regarded as a core part of one's identity and overwhelmingly perceived as a net positive behaviour. Sample participant resistance training and cardio routines are described in detail within this article.


Asunto(s)
Trastorno Dismórfico Corporal , Adulto , Humanos , Trastorno Dismórfico Corporal/diagnóstico , Trastorno Dismórfico Corporal/complicaciones , Imagen Corporal/psicología , Músculos , Autoimagen , Delgadez
2.
CNS Spectr ; 28(1): 33-40, 2023 02.
Artículo en Inglés | MEDLINE | ID: mdl-34313212

RESUMEN

OBJECTIVE: To assess executive functions (EFs) in patients with body dysmorphic disorder (BDD) and obsessive-compulsive disorder (OCD) compared with healthy controls. METHODS: Adults diagnosed with BDD (n = 26) or OCD (n = 29) according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, and healthy controls (n = 28) underwent validated and computerized neuropsychological tests, spatial working memory (SWM), intra-extra-dimensional set shifting (IED), and stop signal task (SST), from the Cambridge Neuropsychological Test Automated Battery (CANTAB). Test performance was compared between groups, and correlated with standardized symptom severity of BDD and OCD. Significance level was set to P < .05. RESULTS: There were no statistically significant between-group differences on key outcome measures in SWM, IED, or SST. There was a weak positive correlation between symptom severity and test errors on SWM and IED in both OCD and BDD groups; increased clinical severity was associated with more errors in these tests. Furthermore, there was a negative correlation between symptom severity and SST in the BDD group. CONCLUSIONS: Patients with BDD or OCD did not differ from healthy control subjects in terms of test performance; however, there were several statistically significant correlations between symptom severity and performance in those with BDD or OCD. More studies on EFs in BDD and OCD are required to elucidate if there are differences in EFs between these two disorders.


Asunto(s)
Trastorno Dismórfico Corporal , Trastorno Obsesivo Compulsivo , Adulto , Humanos , Trastorno Dismórfico Corporal/diagnóstico , Trastorno Dismórfico Corporal/complicaciones , Trastorno Dismórfico Corporal/epidemiología , Función Ejecutiva , Comorbilidad , Trastorno Obsesivo Compulsivo/epidemiología , Pruebas Neuropsicológicas
3.
Transl Psychiatry ; 12(1): 325, 2022 08 10.
Artículo en Inglés | MEDLINE | ID: mdl-35948537

RESUMEN

In individuals with body dysmorphic disorder (BDD), perceptual appearance distortions may be related to selective attention biases and aberrant visual scanning, contributing to imbalances in global vs. detailed visual processing. Treatments for the core symptom of perceptual distortions are underexplored in BDD; yet understanding their mechanistic effects on brain function is critical for rational treatment development. This study tested a behavioral strategy of visual-attention modification on visual system brain connectivity and eye behaviors. We acquired fMRI data in 37 unmedicated adults with BDD and 30 healthy controls. Participants viewed their faces naturalistically (naturalistic viewing), and holding their gaze on the image center (modulated viewing), monitored with an eye-tracking camera. We analyzed dynamic effective connectivity and visual fixation duration. Modulated viewing resulted in longer mean visual fixation duration compared to during naturalistic viewing, across groups. Further, modulated viewing resulted in stronger connectivity from occipital to parietal dorsal visual stream regions, also evident during the subsequent naturalistic viewing, compared with the initial naturalistic viewing, in BDD. Longer fixation duration was associated with a trend for stronger connectivity during modulated viewing. Those with more severe BDD symptoms had weaker dorsal visual stream connectivity during naturalistic viewing, and those with more negative appearance evaluations had weaker connectivity during modulated viewing. In sum, holding a constant gaze on a non-concerning area of one's face may confer increased communication in the occipital/parietal dorsal visual stream, facilitating global/holistic visual processing. This effect shows persistence during subsequent naturalistic viewing. Results have implications for perceptual retraining treatment designs.


Asunto(s)
Trastorno Dismórfico Corporal , Adulto , Trastorno Dismórfico Corporal/complicaciones , Trastorno Dismórfico Corporal/diagnóstico , Encéfalo/diagnóstico por imagen , Fijación Ocular , Humanos , Imagen por Resonancia Magnética , Percepción Visual
4.
Body Image ; 40: 267-284, 2022 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-35085863

RESUMEN

Adverse childhood experiences (ACEs) are considered a risk factor for the development of various forms of mental disorders, including body dysmorphic disorder (BDD). The aim of the present work was to examine the association between ACEs and BDD symptomatology and to identify features of studies that might moderate this association. We conducted a three-level meta-analysis of 27 articles that included 9167 participants. Results showed that the types of ACE examined (total ACE, abuse, neglect, teasing, and bullying) were positively associated with BDD symptomatology. Specifically, a low to moderate association was found for ACE overall, defined as abuse, neglect, bullying, or teasing (r = 0.289, 95% confidence interval (CI) [.240,.337), for bullying (r = 0.282, 95% CI [.206,.354]), and for abuse (r = 0.223, 95% CI [.169,.276]) were found; and a moderate to large association was found for experienced teasing (r = 0.423, 95% CI [.360,.482]). In addition, moderator analyses of the association between ACE and BDD symptomatology resulted in a predictive model in which the type of ACE, type of sample, and gender of participants moderated the magnitude of the association between ACEs and BDD symptomatology.


Asunto(s)
Experiencias Adversas de la Infancia , Trastorno Dismórfico Corporal , Acoso Escolar , Maltrato a los Niños , Trastorno Dismórfico Corporal/complicaciones , Trastorno Dismórfico Corporal/diagnóstico , Trastorno Dismórfico Corporal/epidemiología , Imagen Corporal/psicología , Niño , Humanos
5.
Eur Rev Med Pharmacol Sci ; 26(1): 291-297, 2022 01.
Artículo en Inglés | MEDLINE | ID: mdl-35049007

RESUMEN

The SARS-CoV-2 pandemic has profoundly affected the social fabric and the economic and health care viability and functioning of most countries. Aside from its deeply destructive impact on health care systems and national economies, the pandemic has jeopardized people's emotional and psychological well-being as well. The authors aimed to shed a light on how the pandemic has been affecting patients with addiction issues and body dysmorphic disorder (BDD), which is characterized by negative thoughts about appearance and body misperceptions. People with body dysmorphic disorder are in fact at increased risk of developing substance use disorders, and such a destructive association has only been made more severe by pandemic-related restrictions, emotional distress and anxiety, as well as longer exposure to social media and online interactions. This is a major cause for concern, because substance use worsens symptoms of BDD and contributes to unfavorable treatment outcomes.


Asunto(s)
Imagen Corporal/psicología , COVID-19/psicología , Pandemias , Trastornos Relacionados con Sustancias/epidemiología , Trastornos Relacionados con Sustancias/psicología , Ansiedad , Conducta Adictiva/complicaciones , Conducta Adictiva/epidemiología , Conducta Adictiva/psicología , Trastorno Dismórfico Corporal/complicaciones , Trastorno Dismórfico Corporal/epidemiología , Trastorno Dismórfico Corporal/psicología , Humanos , Medios de Comunicación Sociales , Trastornos Relacionados con Sustancias/complicaciones
6.
Soc Cogn Affect Neurosci ; 17(4): 430-436, 2022 04 01.
Artículo en Inglés | MEDLINE | ID: mdl-34673984

RESUMEN

A number of psychiatric disorders, including body dysmorphic disorder (BDD), anorexia nervosa, bulimia nervosa, and social anxiety disorder, are characterized by heightened appearance concerns and increased cognitive and perceptual biases toward one's own physical appearance. In the present study, we examined individual differences in self-reported appearance anxiety and symptoms of BDD in relation to the late positive potential (LPP)-an index of stimulus significance-in response to pictures of oneself, strangers and objects among 83 female college students. The results indicated that the LPP was larger for pictures of oneself compared to pictures of strangers and objects. Further, the Yale-Brown Obsessive-Compulsive Scale Modified for Body Dysmorphic Disorder and Appearance Anxiety Inventory scales both related to an increased LPP to pictures of oneself but not to strangers or objects. The findings suggest that the LPP elicited by pictures of oneself may function as a neural marker of appearance concerns, which could be leveraged to study the development and maintenance of a range of psychiatric disorders characterized by increased appearance concerns.


Asunto(s)
Anorexia Nerviosa , Trastorno Dismórfico Corporal , Ansiedad , Trastornos de Ansiedad/psicología , Trastorno Dismórfico Corporal/complicaciones , Trastorno Dismórfico Corporal/diagnóstico , Trastorno Dismórfico Corporal/psicología , Femenino , Humanos , Autoinforme
7.
J Behav Ther Exp Psychiatry ; 73: 101674, 2021 12.
Artículo en Inglés | MEDLINE | ID: mdl-34242980

RESUMEN

BACKGROUND AND OBJECTIVES: Previous research has indicated that body dysmorphic disorder (BDD) and obsessive-compulsive disorder (OCD) often demonstrate similar cognitive impairments across multiple domains. However, findings for both disorders have not consistently shown impaired cognition. As such, BDD and OCD might share an overlapping pattern of cognitive heterogeneity, characterised by subgroups with different cognitive profiles. METHODS: To evaluate this possibility, we compared 26 BDD, 24 OCD, and 26 healthy control participants on a comprehensive eight-domain cognitive battery. Then, cluster analysis was performed on the BDD and OCD participants' combined data to explore for cognitive subgroups. RESULTS: No significant differences were found between the three groups' cognitive functioning, except for poorer visual learning in OCD relative to healthy controls. Cluster analysis produced two cognitive subgroups within the combined BDD and OCD data, characterised by intact cognition (52%) and broadly impaired cognition (48%). Each subgroup comprised both BDD and OCD participants, in similar proportions. The subgroups did not differ in clinical or demographic features. LIMITATIONS: Sample sizes were moderate. Future research should investigate clustering patterns both in larger groups and separately in BDD and OCD samples to determine replicability. CONCLUSIONS: These findings suggest that BDD and OCD may involve similar patterns of cognitive heterogeneity, and further imply that individuals with either disorder can show a wide range of cognitive profiles, thus necessitating a nuanced approach to future cognitive research in BDD and OCD.


Asunto(s)
Trastorno Dismórfico Corporal , Trastorno Obsesivo Compulsivo , Trastorno Dismórfico Corporal/complicaciones , Cognición , Humanos , Trastorno Obsesivo Compulsivo/complicaciones
8.
Forensic Sci Int ; 325: 110872, 2021 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-34147938

RESUMEN

Silicone embolism syndrome (SES) is a well known complication after injection of silicone gel as well as liquid silicone. Rarely, men use physiologic salt solution or liquid silicone injected into the subcutaneous tissue of the scrotum, the penis, the upper genital or the inguinal region. Those men, who call themselves "siliconers", want to get a larger penis and scrotum, also visible when wearing clothes. Injections of liquid silicone in the mentioned regions can lead to liquid silicone embolism in the lungs and also the liver, sometimes eventually leading to death via right heart failure as in the present case. Autopsy revealed "frog spawn"-like vacuoles in the subcutaneous tissue of the genital region and liquid silicone embolism in lungs and liver. Additionally, toxicological analyses revealed different liquid silicones. Smaller oligomers were transported into lung and liver, larger ones showed local enrichment at the injection site. The seized Polydimethylsiloxane (PDMS) could not be detected in abdominal fat, blood or urine, potentially due to low perfusion of fat tissue, the aqueous character of blood and urine or the time span between last injection and death.


Asunto(s)
Enfermedad Hepática Inducida por Sustancias y Drogas/patología , Embolia/inducido químicamente , Embolia Pulmonar/inducido químicamente , Siliconas/efectos adversos , Adulto , Trastorno Dismórfico Corporal/complicaciones , Embolia/patología , Humanos , Inyecciones Subcutáneas , Hígado/patología , Pulmón/patología , Masculino , Embolia Pulmonar/patología , Vacuolas
9.
Laryngoscope ; 131(9): E2518-E2524, 2021 09.
Artículo en Inglés | MEDLINE | ID: mdl-33729598

RESUMEN

OBJECTIVES/HYPOTHESIS: To evaluate the role of body dysmorphic disorder (BDD) in patients with postparalytic facial nerve syndrome with synkinesis (PFS). STUDY DESIGN: A single-center retrospective cohort study. METHODS: A total of 221 adults (74% women; median age: 44 years; median duration since onset of facial palsy: 1.6 years) were included. To diagnose BDD, the BDD Munich Module was used. Associations with House-Brackmann grading, Stennert index grading, Facial Clinimetric Evaluation (FaCE) survey, Facial Disability Index (FDI), general quality of life (SF-36), Beck Depression Inventory (BDI), and the Liebowitz Social Anxiety Scale (LSAS) was analyzed. RESULTS: A total of 59 patients (27%) were classified as patients with BDD. Significant associations were found between the diagnosis of BDD and female gender and lower FDI, FaCE, and SF-36 scores and higher BDI and LSAS scores. Multivariate analysis revealed BDI, FaCE total score, and FaCE social function subscore as independent factors associated with BDD. CONCLUSION: BDD was a relevant diagnosis in patients with PFS. A higher BDD level was associated with general and facial-specific quality of life and more psychosocial disabilities. Optimal treatment of PFS has to include these nonmotor dysfunctions. LEVEL OF EVIDENCE: 3 Laryngoscope, 131:E2518-E2524, 2021.


Asunto(s)
Trastorno Dismórfico Corporal/complicaciones , Parálisis Facial/diagnóstico , Sincinesia/diagnóstico , Adulto , Evaluación de la Discapacidad , Femenino , Humanos , Masculino , Escalas de Valoración Psiquiátrica , Calidad de Vida , Estudios Retrospectivos , Índice de Severidad de la Enfermedad , Factores Sexuales
10.
Aust N Z J Psychiatry ; 55(4): 381-390, 2021 04.
Artículo en Inglés | MEDLINE | ID: mdl-33637003

RESUMEN

OBJECTIVE: Current understanding of cognitive functioning in body dysmorphic disorder is limited, owing to few studies, small sample sizes and assessment across only limited cognitive domains. Existing research has also shown inconsistent findings, with both intact and impaired cognition reported in body dysmorphic disorder, which might point towards cognitive heterogeneity in the disorder. This study aimed to examine the cognitive profile of body dysmorphic disorder in a large sample across eight cognitive domains, and to explore whether cognitive subgroups might be identified within body dysmorphic disorder. METHOD: Cognitive domains of inhibition/flexibility, working memory, speed of processing, reasoning and problem-solving, visual and verbal learning, attention/vigilance and social cognition were assessed and compared between 65 body dysmorphic disorder patients and 70 healthy controls. Then, hierarchical clustering analysis was conducted on the body dysmorphic disorder group's cognitive data. RESULTS: Group-average comparisons demonstrated significantly poorer cognitive functioning in body dysmorphic disorder than healthy controls in all domains except for attention/vigilance and social cognition. Cluster analysis identified two divergent cognitive subgroups within our body dysmorphic disorder cohort characterised by (1) broadly intact cognitive function with mild selective impairments (72.3%), and (2) broadly impaired cognitive function (27.7%). However, the clusters did not significantly differ on clinical parameters or most sociodemographic characteristics. CONCLUSION: Our findings demonstrate considerable cognitive heterogeneity among persons with body dysmorphic disorder, rather than uniform deficits. Poor performances in the broadly impaired subgroup may have driven group-level differences. However, our findings also suggest a dissociation between cognitive functioning and clinical characteristics in body dysmorphic disorder that has implications for current aetiological models. Additional research is needed to clarify why some people with body dysmorphic disorder demonstrate cognitive deficits while others do not.


Asunto(s)
Trastorno Dismórfico Corporal , Trastornos del Conocimiento , Trastorno Dismórfico Corporal/complicaciones , Cognición , Humanos , Memoria a Corto Plazo , Pruebas Neuropsicológicas , Aprendizaje Verbal
11.
Rev. andal. med. deporte ; 13(3): 140-143, sept. 2020. tab
Artículo en Portugués | IBECS | ID: ibc-199825

RESUMEN

OBJETIVO: O objetivo deste estudo foi de verificar se há correlação entre dismorfia muscular, dependência de exercício e overtraining em praticantes de musculação. MÉTODO: Participaram do estudo 320 sujeitos, maiores de idade, praticantes de musculação há, pelo menos, três meses, com freqüência mínima de três treinos semanais, de dez diferentes academias, os quais foram avaliados por meio de três questionários, validados, relacionados aos temas da pesquisa, além do questionário de caracterização da amostra. RESULTADOS: A partir da análise dos dados, verificou-se correlação moderada entre dismorfia muscular e dependência de exercício e correlação fraca entre dependência de exercício e overtraining. CONCLUSÃO: Indivíduos com risco para dismorfia muscular tendem a apresentar maior risco para o desenvolvimento da dependência de exercício


OBJETIVO: El objetivo de este estudio fue verificar si existe una correlación entre la dismorfia muscular, la dependencia del ejercicio y el sobreentrenamiento en practicantes de musculación. MÉTODO: Participaron en este estudio 320 sujetos, mayores de 18 años, practicantes de musculación durante al menos tres meses, con una frecuencia mínima de tres entrenamientos semanales, provenientes de diez gimnasios diferentes, que se evaluaron mediante tres cuestionarios validados relacionados con el Temas de investigación, además del cuestionario de caracterización de la muestra. RESULTADOS: Del análisis de los datos, hubo una correlación moderada entre la dismorfia muscular y la dependencia del ejercicio y una débil correlación entre la dependencia del ejercicio y el sobreentrenamiento. CONCLUSIÓN: Las personas con riesgo de dismorfia muscular tienden a tener un mayor riesgo de desarrollar dependencia al ejercicio


OBJECTIVE: The aim of this study was to verify if there is a correlation between muscle dysmorphia, exercise dependence and overtraining in gym goers. METHOD: The study included 320 subjects, aged, gym goers for at least three months, with a minimum frequency of three weekly workouts, from ten different gyms, which were evaluated through three validated questionnaires related to the subjects of the besides the sample characterization questionnaire. RESULTS: From the data analysis, there was a moderate correlation between muscle dysmorphia and exercise dependence and a weak correlation between exercise dependence and overtraining. CONCLUSION: Individuals at risk for muscle dysmorphia tend to be at higher risk for developing exercise dependence


Asunto(s)
Humanos , Masculino , Femenino , Adulto Joven , Adulto , Persona de Mediana Edad , Anciano , Trastorno Dismórfico Corporal/complicaciones , Conducta Adictiva/complicaciones , Ejercicio Físico/psicología , Entrenamiento de Fuerza/estadística & datos numéricos , Dependencia Psicológica
12.
Pediatr Dermatol ; 37(5): 896-899, 2020 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-32643246

RESUMEN

We report the case of an adolescent with hypohidrotic ectodermal dysplasia, who had obsessive-compulsive disorder and was later diagnosed with body dysmorphic disorder (BDD). BDD is a highly distressing, adolescent-onset disorder that may lead to social isolation, the development of comorbid mental health disorders and suicidality. Patients typically lack insight into their BDD and frequently present to dermatologists for medical treatment. In this paper, we address the challenges faced when working with patients with BDD.


Asunto(s)
Trastorno Dismórfico Corporal , Displasia Ectodermal Anhidrótica Tipo 1 , Trastorno Obsesivo Compulsivo , Adolescente , Trastorno Dismórfico Corporal/complicaciones , Trastorno Dismórfico Corporal/diagnóstico , Comorbilidad , Displasia Ectodermal Anhidrótica Tipo 1/complicaciones , Displasia Ectodermal Anhidrótica Tipo 1/diagnóstico , Humanos , Trastorno Obsesivo Compulsivo/epidemiología
13.
BMC Psychiatry ; 20(1): 69, 2020 02 18.
Artículo en Inglés | MEDLINE | ID: mdl-32070300

RESUMEN

BACKGROUND: Although effective treatments are available, most individuals with body dysmorphic disorder (BDD) do not receive an appropriate diagnosis or treatment. We aimed to examine treatment utilization and barriers to treatment, and to identify associated socio-demographic and clinical characteristics. METHODS: German individuals completed an online self-report survey of appearance concerns. A sample of N = 429 individuals met criteria for BDD. We examined the frequency of treatment utilization and barriers, analyzed comparisons between treated and untreated individuals and assessed the relationships of socio-demographic and clinical features with mental health treatment utilization and treatment barriers, respectively. RESULTS: Only 15.2% of the individuals with BDD had been diagnosed with BDD, and lifetime rates of mental health treatment were low (39.9%). Individuals endorsed multiple barriers to mental health treatment, especially shame, low perceived need and a preference for cosmetic and medical treatments. Associated features were identified, including age, a BDD diagnosis, body dysmorphic symptom severity, a likely major depressive disorder, prior cosmetic surgery, and insight. CONCLUSIONS: The results of this largest study to date highlight that BDD is still underrecognized and undertreated even in a country with extensive mental health care and few financial barriers. We discuss modifiable factors and strategies to foster awareness of BDD in sufferers and professionals to improve treatment dissemination and to reduce treatment barriers.


Asunto(s)
Trastorno Dismórfico Corporal/psicología , Trastorno Dismórfico Corporal/terapia , Adolescente , Adulto , Anciano , Trastorno Dismórfico Corporal/complicaciones , Trastorno Dismórfico Corporal/diagnóstico , Trastorno Depresivo Mayor/complicaciones , Femenino , Alemania , Humanos , Masculino , Persona de Mediana Edad , Prevalencia , Autoinforme , Encuestas y Cuestionarios , Adulto Joven
14.
J Eur Acad Dermatol Venereol ; 34(2): 370-376, 2020 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-31515838

RESUMEN

BACKGROUND AND OBJECTIVE: Body dysmorphic disorder (BDD) is a mental disorder that is difficult to diagnose, causes a lot of suffering and is more prevalent in dermatology patients than in the general population. Our objective was to screen for possible cases of BDD in patients with acne and to determine the prevalence according to DSM-IV and DSM-5 criteria, as well as to analyse the relationship between dermatological and sociodemographic variables. METHODS: A total of 245 patients diagnosed with acne in 11 dermatological centres in Spain were included in the study by members of the Aragon Psychodermatology Research Group and Spanish Research Group of Psychiatric Dermatology. We used the Body Dysmorphic Disorder Questionnaire (BDDQ) as a screening tool. RESULTS: In our sample, we obtained a prevalence for BDD of 10.6% (95% CI: 7.6-13.6%). The prevalence was the same with DSM-IV or DSM-5 criteria. Possible cases of BDD were predominantly women (P = 0.021), and 56% had non-inflammatory lesions vs. 30% of negative patients (P = 0.002). Positive patients as possible cases of BDD spent more than two hours on average a day worrying about their appearance. Most people only worried about one part of their body (86%), and in 95% of the cases, the part of their body that worried them was the face. The three most frequent compulsive behaviours in patients who screened positive for BDD were mirror checking (90.7%), camouflaging (79.1%) and using make-up (72.1%). CONCLUSIONS: As a consequence of the high prevalence of possible cases of BDD in patients with acne observed in our study, there is a need for dermatologists to screen for BDD so that they can be referred to a mental health unit to confirm the diagnosis and be offered treatment to reduce the progression of psychosocial deterioration and the development of comorbid disorders.


Asunto(s)
Acné Vulgar/complicaciones , Trastorno Dismórfico Corporal/psicología , Acné Vulgar/psicología , Adolescente , Adulto , Trastorno Dismórfico Corporal/complicaciones , Trastorno Dismórfico Corporal/epidemiología , Femenino , Humanos , Masculino , Prevalencia , España/epidemiología , Encuestas y Cuestionarios , Adulto Joven
15.
Ital J Pediatr ; 45(1): 159, 2019 Dec 04.
Artículo en Inglés | MEDLINE | ID: mdl-31801583

RESUMEN

BACKGROUND: Mutations in Proline-rich Transmembrane Protein 2 (PRRT2) have been primarily associated with individuals presenting with infantile epilepsy, including benign familial infantile epilepsy, benign infantile epilepsy, and benign myoclonus of early infancy, and/or with dyskinetic paroxysms such as paroxysmal kinesigenic dyskinesia, paroxysmal non-kinesigenic dyskinesia, and exercise-induced dyskinesia. However, the clinical manifestations of this disorder vary widely. PRRT2 encodes a protein expressed in the central nervous system that is mainly localized in the pre-synaptic neurons and is involved in the modulation of synaptic neurotransmitter release. The anomalous function of this gene has been proposed to cause dysregulation of neuronal excitability and cerebral disorders. CASE PRESENTATION: We hereby report on a young child followed-up for three years who presents with a spectrum of clinical manifestations such as congenital microcephaly, dysmorphic features, severe intellectual disability, and drug-resistant epileptic encephalopathy in association with a synonymous variant in PRRT2 gene (c.501C > T; p.Thr167Ile) of unknown clinical significance variant (VUS) revealed by diagnostic exome sequencing. CONCLUSION: Several hypotheses have been advanced on the specific role that PRRT2 gene mutations play to cause the clinical features of affected patients. To our knowledge, the severe phenotype seen in this case has never been reported in association with any clinically actionable variant, as the missense substitution detected in PRRT2 gene. Intriguingly, the same mutation was reported in the healthy father: the action of modifying factors in the affected child may be hypothesized. The report of similar observations could extend the spectrum of clinical manifestations linked to this mutation.


Asunto(s)
Trastorno Dismórfico Corporal/diagnóstico , Estudios de Asociación Genética , Predisposición Genética a la Enfermedad , Proteínas de la Membrana/genética , Microcefalia/diagnóstico , Proteínas del Tejido Nervioso/genética , Convulsiones/genética , Trastorno Dismórfico Corporal/complicaciones , Pruebas Genéticas/métodos , Humanos , Lactante , Imagen por Resonancia Magnética/métodos , Masculino , Microcefalia/complicaciones , Mutación Missense/genética , Pronóstico , Enfermedades Raras , Medición de Riesgo , Convulsiones/complicaciones , Índice de Severidad de la Enfermedad
16.
J Psychiatr Pract ; 25(6): 427-436, 2019 11.
Artículo en Inglés | MEDLINE | ID: mdl-31821219

RESUMEN

Drug use disorders (DUDs) are highly prevalent in body dysmorphic disorder (BDD), but motives for illicit drug use in BDD have not yet been explored. This study examined motives for drug use and clinical correlates of drug use motives in a sample of individuals with BDD and lifetime drug use, using the Drug Use Motives Questionnaire and 3 additional body image-specific drug use motives. As predicted, the Drug Use Motives Questionnaire coping motive was positively associated with attempted suicide and a lifetime DUD. All 3 body image-specific motives for drug use were also significantly associated with a lifetime DUD. In addition, they were the only variables that were significantly associated with greater severity of BDD. These results build on previous evidence suggesting that coping motives are related to problematic substance use and suicide attempts in BDD.


Asunto(s)
Trastorno Dismórfico Corporal/complicaciones , Trastorno Dismórfico Corporal/psicología , Drogas Ilícitas , Motivación , Trastornos Relacionados con Sustancias/complicaciones , Trastornos Relacionados con Sustancias/psicología , Adulto , Femenino , Humanos , Estudios Longitudinales , Masculino , Estudios Prospectivos , Encuestas y Cuestionarios
17.
Clin Psychol Rev ; 74: 101771, 2019 12.
Artículo en Inglés | MEDLINE | ID: mdl-31751876

RESUMEN

Body image disturbance is an important feature of Anorexia Nervosa (AN). Some researchers have argued that body image disturbance is not just a symptom of AN, but plays a causal role in the development, persistence, and relapse of AN. Our aim was to systematically review the existing empirical evidence concerning the role of the cognitive-affective, perceptual, and behavioral components of body image disturbance in AN. 46 studies fulfilled eligibility criteria reporting about 4928 participants with AN. There is some evidence suggesting that body image disturbance is related to the course of AN. However, experimental studies were missing and operationalizations of body image constructs and AN outcome measures varied greatly across studies. Therefore, on the basis of the available empirical data, it remained unclear whether body image disturbance is indeed a causal risk factor for AN. For future studies, it is crucial to use more consistent terminology and more specific and precise definitions of body image constructs as well as experimental designs, adequately powered samples, and well-validated measures. Altogether, this would set the stage to generate the high-quality data that are necessary to clarify the role of body image disturbance in the onset, maintenance and relapse of AN.


Asunto(s)
Anorexia Nerviosa/fisiopatología , Trastorno Dismórfico Corporal/fisiopatología , Anorexia Nerviosa/etiología , Trastorno Dismórfico Corporal/complicaciones , Humanos
18.
PLoS One ; 14(7): e0219791, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31344065

RESUMEN

Rituals, such as gazing at faces, are common in body dysmorphic disorder (BDD) and appear in cognitive-behavioral models as a maintaining factor. Rituals are also common in obsessive-compulsive disorder (OCD). In contrast to OCD, the proposed associations between rituals and intrusive thoughts/appearance preoccupation have not been empirically investigated for BDD. We examined if the assumed effect of gazing rituals on attractiveness ratings exists and if it is associated with dissociation. In an experiment, we asked N = 65 non-clinical females to focus on the nose of a photographed face at pre- and post-test. In between, participants gazed at the nose of either the same (relevant gazing) or another face (irrelevant gazing). We found increasing dissociation after gazing in both conditions and a differentially stronger decrease of attractiveness ratings in the relevant gazing condition. Our findings support the hypothesized effect of gazing rituals on attractiveness evaluation in cognitive-behavioral models for BDD.


Asunto(s)
Trastorno Dismórfico Corporal/complicaciones , Trastorno Dismórfico Corporal/fisiopatología , Conducta Ceremonial , Trastornos Disociativos/complicaciones , Trastornos Disociativos/fisiopatología , Fijación Ocular/fisiología , Análisis de Varianza , Teorema de Bayes , Cara , Femenino , Humanos , Cooperación del Paciente , Incertidumbre , Adulto Joven
19.
Rev. bras. cir. plást ; 34(1): 108-112, jan.-mar. 2019.
Artículo en Inglés, Portugués | LILACS | ID: biblio-994559

RESUMEN

O transtorno dismórfico corporal é encontrado com uma certa frequência nos atendimentos relacionados à estética. Entretanto, permanece subdiagnosticado devido à dificuldade de diferenciar uma insatisfação pessoal natural com a imagem corporal de uma queixa patológica. Para os pacientes com TDC, o incômodo gerado pelo seu "defeito" costuma ser desproporcional ao que observamos no exame físico. Além disso, na tentativa de corrigir aquilo que não lhe agrada, ele se submete a diversos procedimentos cirúrgicos que, em grande parte das vezes, considerará insuficiente para a resolução do seu problema. Nesse sentido, buscamos, com este trabalho, ampliar as discussões já existentes na literatura especializada. Assim, assumindo a escassa bibliografia, tencionamos, além de construir discussões acerca dessa afecção, o que pode contribuir para a identificação dos traços desse transtorno, evitando, por conseguinte, a realização de procedimentos cirúrgicos desnecessários e nortear as ações do especialista no que diz respeito à possibilidade de uma disputa judicial.


Body dysmorphic disorder (BDD) is found with a certain frequency in aesthetic-related care. However, it is underdiagnosed due to the difficulty in differentiating a personal dissatisfaction with body image of a pathological complaint. For BDD patients, the discomfort generated by their "defect" is often disproportionate to that observed on physical examination. In addition, in an attempt to correct their "defect", the patients undergoes various surgical procedures, which are often considered insufficient by the patients to solve their problem. Hence, this study aimed to expand the already existing discussions in the specialized literature. Since there are only a few studies on the topic, we plan to discuss this condition so as to contribute towards identification of the characteristics of this disorder, thus, avoiding unnecessary surgical procedures and guiding the specialist's actions in case of a legal dispute.


Asunto(s)
Masculino , Femenino , Adolescente , Adulto , Persona de Mediana Edad , Pacientes , Cirugía Plástica/métodos , Procedimientos de Cirugía Plástica/efectos adversos , Procedimientos de Cirugía Plástica/métodos , Trastorno Dismórfico Corporal/cirugía , Trastorno Dismórfico Corporal/complicaciones , Trastorno Dismórfico Corporal/fisiopatología , Trastorno Dismórfico Corporal/rehabilitación
20.
Actas dermo-sifiliogr. (Ed. impr.) ; 110(1): 28-32, ene.-feb. 2019. ilus
Artículo en Español | IBECS | ID: ibc-176883

RESUMEN

Introducción: El trastorno dismórfico corporal (TDC) es una enfermedad mental difícil de diagnosticar; puede causar una gran cantidad de sufrimiento, y el tratamiento a menudo es complejo y desafiante. Material y método: La población de estudio comprendía 81 pacientes ambulatorios dermatológicos consecutivos que cumplían los criterios de inclusión para la participación. Fueron tratados en hospitales en zonas urbanas (Zaragoza) y rurales (Alcañiz). Es un estudio piloto prospectivo y observacional. Se utilizaron como instrumentos de evaluación: a) La escala de gradación del acné de Cook y b) El Cuestionario de Trastorno Dismórfico Corporal (Body Dysmorphic Disorder Questionnaire, BDDQ) (traducción al español). Los posibles casos de TDC se identificaron mediante 2 criterios: 1) Un resultado positivo en el BDDQ (4 puntos positivos y una pregunta de exclusión negativa); y 2) Escala de gradación del acné de Cook que reflejó lesiones no perceptibles/leves (los criterios más estrictos) o lesiones moderadas (criterios menos estrictos) Resultados: El rango de edad de los pacientes era de 13 a 43 años. La edad promedio fue 19 con una desviación estándar de 6,2. De los 81 participantes, el 54,3% eran mujeres y el 45,7% eran hombres. El 61,7% vivía en el área rural cubierta por el hospital de Alcañiz y el 38,3% era del área urbana atendida por el Hospital Universitario de Zaragoza. Cuando se aplicaron criterios más restrictivos con respecto a la gravedad de la afección (solo los pacientes con acné leve), el proceso de detección de BDDQ resultó en una tasa de prevalencia de TDC del 8,6% (7 pacientes); si los criterios fueron menos restrictivos (incluidos los pacientes con lesiones moderadas), la tasa fue del 14,8% (12 pacientes). Discusión: Vale la pena recordar que los pacientes con TDC que participaron en este estudio pasan un promedio de 2 h al día pensando y preocupándose por su apariencia. Este hecho es un recordatorio de la importancia de diagnosticar y tratar correctamente el TDC ya que la afección claramente tiene un impacto serio y negativo en las vidas de los afectados


Introduction: Body dysmorphic disorder (BDD) is a mental health condition that is difficult to diagnose; it can cause a great deal of suffering, and treatment is often complex and challenging. Material and method: The study population comprised 81 consecutive dermatology out-patients who met the inclusion criteria for participation. Participants were treated at hospitals in both urban (Zaragoza) and rural areas (Alcañiz). The project was based on a prospective and observational pilot study. Assessment instruments used: Cook's Acne Grading Scale and Body Dysmorphic Disorder Questionnaire (BDDQ) (Spanish translation). Possible cases of BDD were identified by means of 2 criteria: 1) A positive result in the BDDQ (4 positive points and a negative exclusion question); and, 2) A Cook's Acne Grading Score that reflected non-noticeable/mild lesions (the most stringent criteria) or moderate lesions (least stringent criteria). Results: The age range of the patients was from 13 to 43 years old. The average age was 19 with a standard deviation of 6.2. Of the 81 participants, 54.3% were women. 61.7% were seen in a rural hospital (Alcañiz Hospital) and 38.3% in an urban one (University Hospital of Zaragoza). When more restrictive criteria regarding the seriousness of the condition were applied (only patients with mild acne), the BDDQ screening resulted in a positive BDD prevalence rate of 8.6% (7 patients); if the criteria were less restrictive (including patients with moderate lesions), the rate was 14.8% (12 patients)


Asunto(s)
Humanos , Masculino , Femenino , Adolescente , Adulto Joven , Adulto , Trastorno Dismórfico Corporal/diagnóstico , Acné Vulgar/diagnóstico , Proyectos Piloto , Imagen Corporal , Trastorno Dismórfico Corporal/complicaciones , Acné Vulgar/fisiopatología , Atención Ambulatoria , Estudios Prospectivos , Estudio Observacional , Encuestas y Cuestionarios , Grupos de Riesgo , Salud Mental , Autoevaluación Diagnóstica
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